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The Killers typically tune down 1/2 step to Eb, but i don't believe that to be the case with this song. I suppose theoretically, they could have recorded this track in Eb, but there would be no real reason to... and it makes more sense in standard tuning anyways.
Note that the panned-out guitar part at the beginning of the song seems to start out an 8th note late, but sometimes 'straightens out' after the bass enters at bar 8. This part should be played by plucking with three fingers, and releasing fret-hand pressure to get that staccato sound. Similar technique is used in 'Glamorous Indie Rock & Roll'.